منابع مشابه
Stem cells in human reproduction.
Human stemcell researchhasmovedat a rapidpace since pluripotent human embryonic stem cells (hESC) were first derived from the inner cell mass of IVF preimplantation embryos (Thomson et al. 1998). This breakthrough generated much excitement amongst the scientific, medical, and general communities as the potential of hESC and their derivatives for novel cell-based therapies was anticipated. Immun...
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Introduction: The nerve fibers in central nervous system are surrounded by myelin sheet which is formed by oligodendrocytes. Cell therapy based on oligodendrocytes and their precursors transplantation can hold a promising alternative treatment for myelin sheet repair in demyelinating diseases. Methods: Human Dental Pulp Stem Cells (hDPSCs) are noninvasive, autologous and easy available s...
متن کاملStem Cells Application in Modeling of Human Genetic Diseases
The use of animal models in modeling of human genetic disease has many advantages. In some cases, however, this method may not be applicable due to some limitations, such as differences in tissue composition, anatomy and physiology of humans and animals. Isogenic human disease models are a population of cells that are selected or engineered to model a specific genetic disease, in vitro. They ar...
متن کاملEndometrial Stem Cells and Reproduction
Abnormal endometrial function remains a significant cause of implantation failure, recurrent pregnancy loss, and other pathologies responsible for female infertility. The development of novel therapies to treat infertility due to endometrial dysfunction requires an understanding of the latest advancements in endometrial cell biology, such as the role of endometrial stem cells. The remarkable re...
متن کاملReprogramming by cytosolic extract of human embryonic stem cells improves dopaminergic differentiation potential of human adipose tissue-derived stem cells
The extract of pluripotent stem cells induces dedifferentiation of somatic cells with restricted plasticity. In this study, we used the extract of human embryonic stem cells (hESC) to dedifferentiate adipose tissue-derived stem cells (ADSCs) and examined the impact of this reprogramming event on dopaminergic differentiation of the cells. For this purpose, cytoplasmic extract of ESCs was prepare...
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ژورنال
عنوان ژورنال: REPRODUCTION
سال: 2010
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-10-0225